Chris and I went there when we first came down here last year, but we went back in February with Bob and Pam after visiting a couple of the nearby Missions.
We ate at La Gloria, a Mexican restaurant with cool steel sculptures out front, reminiscent of Mexican folk art. The food was ok. I'd like to go back and try a different dish than the "Mexican pizza" I tried that was really just a big tostada loaded down with way too much shredded lettuce. The patio seating is awesome, though, because it's right on the river and it's dog friendly.
We then got delicious ice cream at Lick. It's based out of Austin, but they have a store at The Pearl. The ice cream was extremely expensive, but super tasty. I'd say worth it because you don't have ice cream of this caliber every day.